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Billing code M0221 · Physician & professional

M0221 Medicaid reimbursement rate by state (2026)

Injection, tixagevimab and cilgavimab. Medicaid pays a median of $250.50 for M0221 across 9 states, from $200.00 in Georgia to $255.51 in Colorado.

Data as of Oct 5, 20269 statesEvery rate links to its official source

States publishing
9
National median
$250.50units vary by state
Lowest
$200.00Georgia
Highest
$255.51Colorado
Answer

What does Medicaid pay for M0221?

9 state Medicaid programs publish a fee-for-service rate for M0221. The national median is $250.50 (units differ between states). Colorado pays the most, $255.51, and Georgia the least, $200.00, a 1.3x spread.

State ranking

M0221 rate by state: highest, middle and lowest

One like-for-like fee-for-service rate per state, ranked. The workspace lists all 9 states with every variant, modifier and effective date.

#StateMedicaid rateUnitPer hourManaged-care plans% of Medicare
1Colorado Source · since 2022-07-01$255.51——Not classified—
2New Mexico Source · since 2025-01-01$253.66——Plans must pay at least this—
3Arizona Source · since 2022-10-01$250.50——Plans negotiate; applies out of network—
5New Jersey Source · since 2021-12-08$250.50——Not classified—
8Pennsylvania Source · since 2021-12-08$200.40——Plans negotiate; applies out of network—
9Georgia Source · since 2022-01-01$200.00——Plans negotiate; applies out of network—
See all 9 states for M0221 — start free

3 more states, with every modifier and provider-type variant, rate history and the plan rule in each state. 14-day free trial, no credit card.

  • Source for every rate
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Rates are per the unit shown for each state; units can differ between states. Medicare amounts are computed from the CMS relative value file and locality cost indices; states with several Medicare localities show a range. Confirm rates with the payer before billing.

Track M0221 in your states. Get an alert when any state changes it, with every variant and the managed-care rule.
Guide

How to read this table

  • Order. States are listed from the highest published rate to the lowest. No single unit is shared by 8 or more states for M0221, so the order is by published amount and is not a like-for-like rank.
  • Medicaid rate. The most the state's fee-for-service program pays for one unit, as published. 2 of the 9 states list more than one rate for M0221, by modifier, provider type or setting; the table shows the one that matches the provider level and setting used across states, without add-ons.
  • Unit. None of the 9 schedules prints a separate unit for M0221, so each amount is a flat payment for one service as the code defines it.
  • Per hour. M0221 is not billed in time units in these states, so no hourly figure is shown.
  • Managed-care plans. The rule the state sets for its plans on this rate. What each rule means is explained below.
  • % of Medicare. No Medicare physician fee schedule amount is on file for M0221, so there is no percentage.
  • Source and date. Each Source link opens the state's own document; “since” is the date the rate took effect.
Context

Why M0221 rates differ between states

Published rates for M0221 run from $200.00 in Georgia to $255.51 in Colorado, a 1.3x gap in the same unit. Half the states pay more than the median of $250.50 and half pay less. The usual reasons for a spread like this in physician & professional rates:

  • Each state sets its own physician conversion factor or fee for every code, and many update them on a state budget cycle rather than on Medicare's calendar.
  • Many schedules pay differently by place of service (office versus facility) and by practitioner, and nurse practitioners and physician assistants are often paid a percentage of the physician amount.
  • Modifiers such as professional or technical component, bilateral, multiple procedure and assistant at surgery change the amount paid, and states apply them with their own percentages.

Timing matters too. None of the states changed its rate for M0221 in 2026, while 6 states still pay a rate that took effect in 2022 or earlier. A state that has not updated its rate in years will drift down the ranking as others raise theirs.

Managed care

What managed-care plans pay for M0221

What a plan pays for M0221 is negotiated privately, but the state decides how much room there is to negotiate. Here is how the rules break down across the 9 states.

In 2 states, the published rate binds plans: a floor, a pass-through or a state-set rate. In 5 states, plans negotiate and the published rate is a benchmark or out-of-network default. The rule for the remaining 2 states is not classified yet.

  • Plans negotiate; the published rate applies out of network (5 states). In-network rates can be above or below the published rate. The published rate is the benchmark both sides know, and the fallback if no contract is signed.
  • Plans must pay at least the published rate (2 states). The published rate is your floor. Negotiate up from it, and if a plan pays less, the contract provision is the basis for a payment dispute.

Plan-negotiated rates are never estimated here. To see the rule and its citation for a particular state, open that state's managed-care page, for example Colorado managed care.

Billing

Units and billing for M0221

M0221 is a billing code in the physician & professional line, billed mostly by physicians, nurse practitioners, physician assistants and other licensed practitioners. This code is billed per service as the state's schedule defines it.

Where a state publishes separate facility and non-facility amounts, the non-facility (office) amount is usually higher because the practice carries the overhead. Practitioners who are not physicians are often paid a reduced percentage of the published amount, so check the schedule for the reduction that applies to your provider type.

Before billing, confirm the rate, unit and any modifier with the state's current schedule or the plan: the amounts here are as published, not a guarantee of payment.

FAQ

Frequently asked questions

What does Medicaid pay for M0221?

It depends on the state. Of the 9 states with a published fee-for-service rate, the median is $250.50. Colorado pays the most ($255.51) and Georgia the least ($200.00).

Which state pays the highest Medicaid rate for M0221?

Colorado, at $255.51, effective 2022-07-01.

Which state pays the lowest Medicaid rate for M0221?

Georgia, at $200.00, effective 2022-01-01.

What unit is M0221 billed in?

None of the 9 schedules prints a separate unit for M0221, so each amount is a flat payment for one service as the code defines it.

Do managed-care plans pay the same rate for M0221?

Not necessarily. In 2 states, the published rate binds plans: a floor, a pass-through or a state-set rate. In 5 states, plans negotiate and the published rate is a benchmark or out-of-network default. The rule for the remaining 2 states is not classified yet. Each rule is cited to the plan contract, statute or notice in the workspace.